Bregar A, et al. - A scoring system, that is proposed to predict gross residual disease at primary debulking surgery (PDS) for advanced epithelial ovarian cancer, has been investigated for reproducibility and prognostic significance when applied to women undergoing neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS). In this retrospective cohort study of 76 patients, two radiologists blinded to outcomes independently assessed change in tumor burden using computed tomography (CT) at diagnosis (T0) and after initiation of NACT but before IDS (T1) using two read criteria: a scoring system utilizing clinical and radiologic criteria and RECIST 1.1. OS or PFS could not be predicted with either predictive score or RECIST 1.1 assessment. As per findings, a change in the score before and after neoadjuvant chemotherapy reduces reader variability and predicts surgical outcome.