Ghiasvand R, et al. - Researchers investigated how phenotypic features and pattern of UV radiation exposure influence the risk of melanoma on different body sites. They used data on 161,540 participants of the Norwegian Women and Cancer study, a population-based prospective study established in 1991 with exposure information collected by questionnaires at baseline and every 4 to 6 years during follow-up through 2015. Among melanoma sites, they noted significant differences in associations with large asymmetric nevi, sunbathing vacations, and indoor tanning. Skin color, hair color, small symmetric nevi, residential ambient UV radiation, and sunburns were noted to be correlated with melanoma risk on all sites. Outcomes thereby support the evidence of divergent pathways to melanoma and indicate similar risk profiles for lower limb and trunk melanomas and for upper limb and head and neck melanomas.