Misra D, et al. - Investigators assessed 1,653 candidates to examine the relationship between body composition categories based on fat and muscle mass and the risk of incident knee osteoarthritis (OA). They categorized study participants as obese nonsarcopenic (obese), sarcopenic obese, sarcopenic nonobese (sarcopenic), or nonsarcopenic nonobese (the referent category) according to their body composition from whole-body dual x-ray absorptiometry. They observed the risk of incident radiographic knee OA among obese women, obese men, and sarcopenic obese women, but not among sarcopenic obese men.