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Mortality in people with dementia, delirium, and unspecified cognitive impairment in the general hospital: Prospective cohort study of 6,724 patients with 2 years follow-up

Clinical Epidemiology Dec 02, 2018

Hapca S, et al. - In this prospective cohort study, researchers investigated mortality in older people with dementia, delirium, and unspecified cognitive impairment during acute hospital admission. Study participants were 6,724 people aged ≥65 years with a structured cognitive assessment on acute admission. In older people with cognitive spectrum disorder (CSD) [defined as delirium alone, known dementia alone, delirium superimposed on known dementia, or unspecified cognitive impairment], mortality post-admission was high. In those with delirium, the immediate risk was highest, while dementia or unspecified cognitive impairment was related to a medium to long-term risk. The study findings suggested that people without dementia who develop delirium were more seriously ill than people with pre-existing brain pathology (dementia).
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