Lilamand M, et al. – Researchers conducted a longitudinal study to investigate the evolution of instrumental activity of daily living (IADL) performance according to the presence of the brain amyloid deposition in community-dwelling individuals aged ≥ 70 years without dementia (N=269). Between baseline and 36 months, amyloid-negative participants had statistically significant improvement in the Activity of Daily Living Prevention Instrument total score. No significant difference after 3 years between amyloid-positive and -negative participants was noted. Results of this study suggested that amyloid-positive and -negative older adults are likely to have different trajectories in IADL performance.