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Severe liver failure rather than cirrhosis is associated with mortality in patients with infectious endocarditis: A retrospective case–control study

European Journal of Gastroenterology & Hepatology Sep 13, 2018

Allaire M, et al. - In patients with liver cirrhosis (LC), researchers described the characteristics and predictors of mortality from infectious endocarditis (IE) via retrospectively selecting 101 individuals with LC and 101 controls with IE matched for sex, age, date of IE, and diabetes in 23 liver units between 2000 and 2013. Results showed that causes of cirrhosis were excess alcohol intake (79.6%), viral hepatitis (17.3%), and metabolic syndrome (14.3%). The strongest predictive factor of mortality related to IE in LC was a severe liver failure but not cirrhosis. Findings suggested that use of aminosides and rifamycin should be reassessed in LC, and cardiac surgery should be considered for selected individuals.

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