Ahmed H, et al. - In this retrospective cohort study, researchers tested the effectiveness of antibiotic prophylaxis for preventing recurrent urinary tract infections (UTIs) in older adults. Analysis of health records as well as prescription records from 19,696 adults aged ≥65 with recurrent UTIs was performed in order to ascertain ≥3 months’ prophylaxis with trimethoprim, cefalexin or nitrofurantoin. Estimation of hazard ratios (HR) and 95% confidence intervals (CI) for risks of clinical recurrence (primary outcome), acute antibiotic prescribing and hospitalisation, was done by using random effects Cox recurrent event models. Findings showed lower rates of UTI recurrence and acute antibiotic prescribing in older adults in relation to antibiotic prophylaxis.