Daugirdas JT - The researcher used archived data from the HEMO study in order to assess changes in total protein concentration during and shortly after a dialysis treatment. According to the observations, on average, regardless of dialysate to serum sodium gradient, the change in plasma volume due to fluid removal was similar to the modeled change in total body water (urea space) after equilibration. The previously reported findings that during dialysis with ultrafiltration, plasma volume contracts to a lesser degree than the interstitial volume and that some fluid may be removed from spaces other than the extracellular fluid, are supported by the results of this study.