van der Thiel M, et al. - This study determined the impact of imaging parameters in multidelay arterial spin-labeling on estimated cerebral blood flow measurements as well as directly compared 3-delay vs 7-delay sequences, evaluating the difference in the estimated transit time and blood flow. Participants in the study were 87 cognitively healthy controls. They found that the 7-delay sequence estimated a higher CBF value than the 3-delay for the transit time–uncorrected and transit time–corrected maps in regions corresponding to the watershed areas. This investigation supported the necessity of standardizing acquisition parameters in multidelay arterial spin-labeling and identifying basic parameters as a confounding factor in CBF quantification studies. In addition, highlighted the importance of applying arterial transit time correction.