Influence of 3 calcium channel blockers on gingival overgrowth in a population of severe refractory hypertensive patients
Journal of Periodontal Research Aug 18, 2018
Vidal F, et al. - In patients with a diagnosis of severe refractory hypertension, authors evaluated the correlation between 3 different calcium channel blockers (CCBs) (nifedipine, amlodipine, and felodipine) and gingival overgrowth. Findings suggested an association of nifedipine and amlodipine, but not felodipine, with gingival overgrowth in patients with severe refractory hypertension. They noted a 2.5 and 4.0 times more likeliness of the patients with gingival to be taking nifedipine and amlodipine, respectively, vs patients without gingival overgrowth. On the other hand, for felodipine this significant association was not observed.
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