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Serum creatinine and Chronic Kidney Disease-Epidemiology estimated glomerular filtration rate: Independent predictors of renal replacement therapy following cardiac surgery

American Journal of Nephrology Aug 18, 2018

Drosos G, et al. - In this prospective cohort study, researchers assessed the impact of preoperative renal function using either estimated-glomerular filtration rate (eGFR) derived using Chronic Kidney Disease-Epidemiology (CKD-EPI) or serum creatinine alone as a predictor for renal replacement therapy (RRT) post-cardiac surgery. They analyzed postoperative data of all patients who had an elective, urgent, or emergency cardiac surgery between 2012 and 2016 in a single center. Findings revealed that factors that were identified as independent predictors of RRT postoperatively included preoperative renal function, defined by serum creatinine or eGFR by CKD-EPI, NYHA class II–IV, and the number of blood units transfused.
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