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Impact of intra-operative fluid and noradrenaline administration on early postoperative renal function after cystectomy and urinary diversion: A retrospective observational cohort study

European Journal of Anaesthesiology Aug 09, 2018

Furrer MA, et al. - In patients undergoing cystectomy and urinary diversion, researchers assessed risk factors for acute kidney injury (AKI) as well as the influence of noradrenaline and intra-operative hydration regimens on early postoperative renal function. They found no increase in the risk for AKI, consequent to noradrenaline administration. Particularly in older patients, those receiving antihypertensive medication, and those whose surgery was lengthy, a too restrictive approach to administration of crystalloids was found to be related to an increased risk for AKI. Also, longer hospital stay and increased postoperative morbidity were observed in relation to AKI. These observations should be taken into account to improve outcome when addressing peri-operative fluid management.

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