DuMontier C, et al. - Researchers used a prospective cohort design including older women with early-stage breast cancer in order to create a predictive model and risk score for 10-year mortality using medical variables (age, comorbidity), health-related quality of life (HRQOL) measures (10-item Physical Function Index and 5-item Mental Health Index from the Medical Outcomes Study (MOS) 36-item Short-Form Survey; 8-item Modified MOS Social Support Survey), and breast cancer variables (stage, surgery, chemotherapy, endocrine therapy). They found that, independent of traditional breast cancer prognostic variables, the addition of HRQOL measures enabled the prediction of 10-year mortality. These data imply that both HRQOL and survival might be improved by improving physical function, mental health, and social support.