Nemati R, et al. - In 61 obese patients with type 2 diabetes (T2DM), researchers examined the associations between changes in bile acids (BAs), fibroblast growth factor19 (FGF19; fasting and prandial), with changes in body weight, glycemia, and other metabolic variables before and 1 year after randomization to sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB). Findings revealed increases in secondary, unconjugated BAs in association with improvements in HBA_1c (but not weight) were achieved after both RYGB and SG. Thereby indicating manipulation of BA could be a potential strategy for controlling T2DM through weight-independent means.