Paskins Z, et al. - Using primary care records from the UK-based Clinical Practice Research Datalink, a cohort study was conducted to investigate fracture risk in patients with late-onset psoriasis and examine the impact of methotrexate on fracture risk. From 1990 to 2004, people aged 40 years and over with incident (new onset) diagnoses of psoriasis, were identified and followed up until 2015. It was noted that the absolute rate of fracture in psoriasis subjects was 58 per 10,000 person-years (95% CI 55, 61) and 53 per 10,000 person-years in the matched controls. Results revealed that methotrexate use was not correlated with increased risk. In improving fracture risk stratification, identifying additional clinical factors correlated with increased fracture risk was important.