Mitra P, et al. - Authors gauged the potential contribution of PTH (parathyroid hormone) gene polymorphisms in kidney stone disease (KSD), a global clinical problem impacting major burden on public health care system worldwide. This first time report in the world regarding association of PTH gene polymorphisms with KSD suggested that for early detection of KSD and for preventing its occurrence, PTH gene polymorphisms could be used as potential genetic markers. Experts noted a significant association of the two single nucleotide polymorphisms (SNPs) (rs307247 and rs307248) of the 3’ UTR, which were in strong linkage disequilibrium with kidney stone risk in the population of West Bengal, India.