Bedggood P, et al. - Researchers ascertained the extent to which optic nerve tissue is displaced following mild acute elevation of intraocular pressure, and whether clinically accessible measures at the anterior eye can be used as a surrogate for such displacements. Large and rapidly reversible shifts are produced by mild acute elevation of IOP in optic nerve tissue in young, healthy eyes. Results demonstrated an association of the resulting degree, direction and spatial distribution of cup movement with IOP status and corneal thickness, but not corneal hysteresis.