Abell JG, et al. - Researchers conducted this study on participants from the Whitehall II cohort study, to assess the associations of diastolic and systolic blood pressure at age 50, 60, and 70 years with the incidence of dementia. They also investigated any mediating impact of cardiovascular disease (CVD) on this link over the follow-up. For incidence of dementia, electronic health records followed-up until 2017 were analyzed. They found an increased risk of dementia, which was independent of CVD, was related to systolic blood pressure ≥130 mmHg at age 50, which is below the conventional ≥140 mmHg threshold used to define hypertension.