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Association of acute depressive symptoms and functional connectivity of emotional processing regions following sport-related concussion

NeuroImage: Clinical May 25, 2018

McCuddy WT, et al. - Researchers attempted to determine the extent to which depressive symptoms following sport-related concussion (SRC) are associated with physiological abnormalities in brain regions associated with emotional processing. For this analysis, 43 concussed collegiate athletes were assessed at approximately one day, one week, and one month post-concussion. They used the Hamilton Rating Scale for Depression (HAM-D) to measure depressive symptoms. According to the findings obtained, connectivity of emotional processing regions was correlated with acute mood disturbance following sport-related concussion. The outcomes suggested that increased connectivity between attention and default mode regions could reflect compensatory mechanisms.
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