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Time-centred approach to understanding risk factors for the progression of CKD

Clinical Journal of the American Society of Nephrology May 24, 2018

Ku E, et al. - Researchers ascertained the median time spent in each of CKD stages 3a–5 and how the time differed according to risk factors related to the progression of the disease. For CKD progression, known risk factors were also related to larger differences in time until progression to the next CKD stage in earlier vs later stages of disease. According to risk factors and stage of the disease, there were marked variations in the time spent in the different stages of CKD. Proteinuria ≥1 g/g, was related to 8 years shorter time spent in stage 3a, 5.6 years shorter time in stage 3b, but only 6 months shorter time in stage 5 vs proteinuria <1 g/g.
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