Zola M, et al. - Experts ascertained the evolution of fundus autofluorescence (FAF) patterns in chronic central serous chorioretinopathy (CSCR) over time. Diffuse hyperautofluorescence was the earliest change in chronic CSCR and it occurred approximately 4 months after the reported first episode. At this stage, the most common change observed was a change within areas of hyperautofluorescence where hyper-reflective dots appeared or disappeared. Results demonstrated a gradual evolution of fundus autofluorescence (FAF) changes in CSCR and so it was not seen to be a good outcome measure for clinical trials.