In chronic spontaneous urticaria, IgE against staphylococcal enterotoxins is common and functional

Allergy Apr 16, 2018

Altrichter S, et al. - In patients with chronic spontaneous urticaria (CSU), researchers determined the prevalence and functional relevance of IgE to Staphylococcus aureus enterotoxins (SEs). A strong correlation of Staphylococcus enterotoxin B (SEB)-IgE levels with disease activity (UASday) was noted in CSU patients. Furthermore, significantly higher basophil histamine release (BHR), in response to SEB, was detected in basophils loaded with the serum of CSU patients vs healthy controls (HCs)...
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General Internal Medicine Dermatology

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