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Immunogenicity of fractional-dose vaccine during a yellow fever outbreak - Preliminary report

New England Journal of Medicine Feb 21, 2018

Ahuka-Mundeke S, et al. - This research was executed in order to gauge the immune response to the fractional dose of yellow fever vaccine in a large-scale campaign. An immune response was elicited from 66% of the subjects who were seropositive at baseline. Maximum individuals who were seronegative at baseline reported the effectiveness of a fractional dose of the 17DD yellow fever vaccine at inducing seroconversion. Hence, the use of fractional-dose vaccination was recommended for outbreak control.
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