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Association between obesity and sperm quality

Andrologia Sep 24, 2017

Ramaraju GA, et al. - An investigation was conducted of the correlation between obesity and sperm quality. The results illustrated the abnormal sperm parameters in obese men based on computer-aided sperm analysis (CASA). Clinicians could need to factor in paternal obesity before assisted reproduction.

Methods

  • The design of this trial was a retrospective cohort study.
  • The enrollees constituted 1285 men with CASA data from our infertility clinic during 2016.

Results

  • A correlation was brought to light between obesity (BMI ≥30) with lower (mean ± SE) volume (-0.28 ± 0.12, p-value = .04), sperm count (48.36 ± 16.51, p-value = .002), concentration (-15.83 ± 5.40, p-value = .01), progressive motility (-4.45 ± 1.92, p-value = .001), total motility (-5.50 ± 2.12, p-value = .002), average curve velocity (μm/s) (-2.09 ± 0.85, p-value = .001), average path velocity (μm/s) (-1.59 ± 0.75, p-value = .006), and higher per cent head defects (0.92 ± 0.81, p-value = .02), thin heads (1.12 ± 0.39, p-value = .007) and pyriform heads (1.36 ± 0.65, p-value = .02).
  • Obese men exhibited a greater tendency for (odds ratio, 95% CI) oligospermia (1.67, 1.15-2.41, p-value = .007) and asthenospermia (1.82, 1.20-2.77, p-value = .005).

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