Iwasaku M, et al. - The goal of this research was to examine characteristics of adrenal crisis (AC) patients, including predisposing diseases and to describe candidate risk factors for AC such as comorbidities and glucocorticoid (GC) therapy. These outcomes describe a review of patients with AC in general practice settings, suggesting that predisposing factors for AC were complicated and that patients other than those with chronic adrenal insufficiency (AI) were older and had more comorbid conditions than those with primary and central AI.