Gaffney KA, et al. – This research inspected the efficacy of peri–training whey protein supplementation combined with mixed–mode interval training (MMIT) in the improvement of glycaemic control among middle–aged men with type–2 diabetes. Significant enhancement in the glycaemic control, following 10–weeks of MMIT, was not clearly advanced with peri–training whey protein supplementation in the study cohort.

Methods

• The scheme of this research was a double-blind randomised controlled trial.
• The enrollmebnt included 24 men (55.7+/-5.6 y) with T2D performed MMIT with whey (20 grams) or placebo control for 10 weeks.
• An analysis was pursued of the glycaemic control through the glucose disposal rate (GDR) during a euglycaemic insulin clamp, fasting blood glucose concentration (FBG), and HOMA-IR.
• In addition, an inspection was conducted of the variations in peak oxygen consumption (VO2peak), 1-repetition maximum strength (1RM), Vastus lateralis (VL) muscle and subcutaneous adipose thicknesses (SAT), and waist circumference (WC).

Results

• 10-weeks of MMIT substantially improved GDR by 27.5% (90%CI 1.2%, 60.7%) and 24.8% (-5.4%, 64.8%) in the whey and control groups, respectively.
• Likely and possible reductions were illustrated in FBG by -17.4% (-30.6%, -1.6) and HOMA-IR by -14.1% (-25.3%, 1.08%) in the whey group.
• Whey effects were not clearly beneficial to glycaemic outcomes, relative to control.
• MMIT also clearly, prominently improved 1RM by 20.6% (16.3%, 24.9%) and 22.7% (18.4%, 27.2%), VO2peak by 22.6% (12.0%, 26.2%) and 18.5% (10.5%, 27.4%), VL muscle thickness by 18.9% (12.0%, 26.2%) and 18.6% (10.5%, 27.4%) and possibly reduced WC by -2.1% (-3.1%, -1.0%) and -1.9% (-3.7%, -0.1%) in the control and whey groups respectively.
• Nevertheless, the whey-control outcome was trivial or unclear.