Lopez DS, et al. – Coffee intake is suggested to have a positive role against chronic diseases. This prospective cohort study investigated the link between coffee intake and incidence of erectile dysfunction (ED). Findings demonstrated no association between coffee intake for a long period of time and risk of ED.

Methods

• Researchers performed a prospective analysis of 21,403 men aged 40-75 years old, using the Health Professionals Follow-Up Study.
• Total coffee, regular and decaffeinated coffee intakes were self-reported on food-frequency questionnaires.
• Questionnaires were performed to assess ED, in 2000, 2004 and 2008.
• To compute hazard ratios (HR) for incident ED (N = 7,298), multivariable adjusted Cox proportional hazards models were used.

Results

• Findings demonstrated no significant differences for incident ED after comparing highest (≥ 4 cups/day) with lowest category (0 cups/day) of total- (HR = 1.00; 95% CI: 0.90 – 1.11) and regular- coffee intakes (HR = 1.00; 95% CI: 0.89 – 1.13).
• For decaffeinated coffee intake, after comparing the highest category with lowest category, researchers found a 37% increased risk of ED (HR = 1.37; 95% CI = 1.08-1.73) with a significant trend (Ptrend = 0.02).
• In addition, stratified analyses revealed an association among current smokers (P_trend = 0.005).