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Transurethral resection of the prostate (TURP) vs GreenLight photoselective vaporization of benign prostatic hyperplasia: Analysis of BPH6 outcomes after 1 year of follow-up

International Journal of Impotence Research: The Journal of Sexual Medicine Aug 25, 2017

Cimino S, et al. – Researchers aimed to compare prostatic GreenLight photovaporization (PVP) to bipolar transurethral resection of the prostate (TURP) with regard to lower urinary tract symptoms (LUTS) improvement through the evaluation of BPH6. The results of this study displayed data in favor of PVP. PVP showed better clinical outcomes while International Prostate Symptoms Score and peak flow improvements were similar.

Methods
  • Researchers included 220 consecutive subjects affected by LUTS.
  • They conducted a propensity score matching using prostate volume, peak flow and International Prostate Symptoms Score (IPSS).
  • They evaluated a sum of 110 (55 TURP and 55 PVP) subjects.

Results
  • They observed after 1 year of follow–up that the rate of subjects resulting in greater BPH6 recovery in the PVP group vs TURP (45.6% vs 18.2%; P=0.001).
  • As evidence accumulates, the TURP treatment displayed greater catheterization time (4.67 vs 1.25; P<0.01) while PVP showed greater recovery experience (82.4 vs 58.2; <0.01).
  • They found postoperative ejaculatory dysfunctions in both groups, 58.8% in TURP and 34.5% in PVP group.
  • The multivariate logistic regression analysis, adjusted for preoperative variables, indicated that PVP was independently associated with BPH6 recovery end point (odds ratio=3.77; P<0.01).
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