Delivanis DA, et al. – An analysis was designed to evaluate the diagnostic performance of unenhanced computed tomography (CT) and18F–fluorodeoxyglucose(18FDG) positron emission tomography(PET)/CT imaging in a high risk population for adrenal malignancy using an optimal reference standard. Researchers exhibited evidence that noncontract CT radiodensity of ≤10 HU excludes malignancy even in a high risk population. For indeterminate adrenal lesions, given a superior specificity, 18FDG PET/CT could be considered as a second stage imaging.