Shang L, et al. – In order to figure out whether vaccine–modified NF–kB and glucocorticoid receptor (GR) signaling in cervicovaginal epithelium correlated with protection, experts conducted this study. In this study, targeting the balance of NF–kB and GR signaling in early cervicovaginal epithelium responses could moderate mucosal inflammation and target cell availability after vaginal infection. In this way, it offered a complementary approach to current prevention strategies.