Costa DN, et al. – This study was undertaken to correlate the anatomical registration of preoperative magnetic resonance imaging (MRI) and prostate whole–mount obtained with 3D–printed, patient–specific, MRI–derived molds (PSM) versus conventional whole–mount sectioning (WMS). It was revealed that the use of PSMs for prostate specimen whole–mount sectioning serves significantly superior anatomical registration of in vivo multiparametric MRI and ex vivo prostate whole–mounts than conventional WMS.