Zhou C, et al. – The role of plasma interleukin (IL)–35 was contemplated here, in the diagnosis and prognosis of prostate cancer (PCa), among Chinese patients undergoing initial prostate biopsy. An association was brought to light between plasma IL–35 levels with PCa. It served as the independent predictor of PCa progression and metastasis. Therefore, IL–35 could be utilized as a potential biomarker for diagnosis and prognosis of PCa. It would also assist in decision making and would predict the stage of the disease.