Canney M, et al. – The association between estimated glomerular filtration rate (eGFR) and overall quality of life (QoL) was explored among older adults. For this group of patients, cystatin C but not creatinine eGFR was associated with clinically modest declines in QoL. By age, this relationship varied. This outcome indicated a contribution of a diminished eGFR little to overall QoL beyond middle age in this population.