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24 vs 72 hours of hypothermia for pediatric cardiac arrest: A pilot, randomized controlled trial

Resuscitation Feb 21, 2018

Fink EL, et al. - Researchers here assessed if 72 vs 24 h of hypothermia (HT) would produce more favorable biomarker profiles after pediatric cardiac arrest (CA). This study reported death of 8 (47%) and 4 (24%) children in the 24 h and 72 h groups. Here, serum neuron specific enolase (NSE) concentration was increased in the 24 vs 72 h group at 84 h–96 h and on day 7. Serum S100b was increased in the 24 h vs 72 h group at 12 h–24 h, 36 h–84 h, and on day 7. Thereby suggesting that serum biomarkers were promising as theragnostic tools in pediatric CA.
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