Given an independent correlation of preexisting renal dysfunction with the risk of cardiac surgery-associated acute kidney injury (AKI), researchers herein investigated if in patients with different levels of baseline renal function, the risk of AKI would be affected by the improvement of postoperative cardiac function after coronary artery bypass grafting (CABG) surgery.

• Researchers enrolled a total of 1,365 patients who underwent CABG surgery and divided them into normal (GFR ≥ 90 ml/min/1.73 m²), non-CKD (60 ≤ GFR < 90 ml/min/1.73 m²), and CKD (GFR < 60 ml/min/1.73 m²) groups.

• The groups had AKI incidence of 22.2%, 28.4%, and 40.6%, respectively.

• Per findings, patients with renal dysfunction and mildly reduced eGFR (60 ≤ GFR < 90 ml/min/1.73 m²) can have reduction in serum creatinine level and reduction in the risk for postoperative AKI following an improvement in cardiac function after CABG surgery.