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Elevated serum concentrations of remnant cholesterol associate with increased carotid intima-media thickness in children and adolescents

The Journal of Pediatrics Jan 21, 2021

Di Costanzo A, Perla FM, D’Erasmo L, et al. - In the present study, the researchers sought to assess the connection between remnant cholesterol and carotid intima-media thickness (cIMT), a surrogate marker for atherosclerosis, in children and adolescents. Seven hundred sixty-seven youths (594, overweight/obese; 173, normal weight) received anthropometric, laboratory, liver and carotid ultrasonographic data. Data reported that the mean concentration of RC was 17.9 ± 10.3 mg/dl and mean cIMT value was 0.51 ± 0.8 mm in the entire cohort. Age, gender, BMI, waist circumference, blood pressure, lipids, liver enzymes, and insulin resistance were significantly associated with remnant cholesterol. A marker of early atherosclerotic damage may be elevated levels of remnant cholesterol in young people.

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