Incidence and impact of parvovirus B19 infection in seronegative solid organ transplant recipients
The Journal of Infectious Diseases Jan 21, 2021
Rezahosseini O, Ekenberg C, Møller DL, et al. - Routine monitoring of Parvovirus B19 (B19V) was conducted in 241 seronegative solid organ transplant (SOT) recipients during the first 6 months posttransplantation. Incidence rates (IR) of 1.2 and 0.21 per 100 recipients per-month, respectively, were observed during the 1st month and the 2nd to 6th months post-transplantation. Six SOT recipients with positive B19V PCR were identified; 3 of these (50%) required hospital admission and 2 (33%) were managed with intravenous immunoglobulin. Hence observations suggest no necessity for routine monitoring of B19V in seronegative SOT recipients. An alternative strategy suggested is targeted screening 1-month post-transplantation and screening upon clinical suspicion.
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