Kim J, Lee HJ, Lee YJ, et al. - For the management of acute pain in various pain-related conditions, a treatment option is ultrasound-guided thoracic paravertebral block (US-TPVB). Via performing this prospective pilot study, researchers evaluated the possible value of US-TPVB as a sympathetic blockade in patients with neuropathic pain disorders in the upper extremities. US-TPVB was performed between the T2 and T3 paravertebral space with 10 mL of 1% mepivacaine in a total of 12 patients. Comparing the ipsilateral and contralateral hands before and after the procedure revealed the median increase in the temperature change of 1.54°C (interquartile range, 1.28– 2.20) between both hands. After the US-TPVB, seven patients (58.3%) exhibited a temperature difference ≥ 1.5°C between both hands. A reduction in pain was observed in 11 patients (91.7%) according to the score on the 11-point numerical rating scale. Findings overall support the possible utility of US-TPVB for sympathetic blockade in patients with upper extremity pain.