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Predictors of technique failure and mortality on peritoneal dialysis: An analysis of New Zealand peritoneal dialysis registry data

Nephrology Dec 03, 2020

Hayat A, et al. - Researchers used the New Zealand Peritoneal dialysis registry to determine the demographic as well as risk predictors of technique failure and mortality among patients receiving peritoneal dialysis (PD). For this purpose, they used a multivariate Cox proportional hazards regression model. The crude technique failure and death rates were estimated to be 165 ± 5.90 and 147.9 ± 5.50 (mean ± SD)/1000 patient‐years, respectively. Hazards of technique failure were found to be lower in older people above 60 years, larger centres, and higher with coiled catheters. Better technique survival was reported in relation to early nephrology referral, continuous ambulatory peritoneal dialysis and Asian ethnicities. The predominant reason for technique failure was infections, with peritonitis being the leading cause (30.2%). Findings revealed multiple factors related to the risk of technique failure, and thus, support the idea of creating a mathematical model for early prediction, for a planned transition to HD.

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