Brisson RT, da Silva Almeida Santos R, Stefano LHSS, et al. - This study was undertaken to explore the relationship between transtemporal window failure on transcranial color-coded Doppler (TCCD) and radiologic findings on computed tomography of the skull along with the demographic features of patients with acute stroke or transient ischemic attack (TIA) and to propose a classification for transcranial window quality on the B-mode scan of TCCD. Researchers recruited a total of 187 consecutive individuals with acute stroke or TIA, of whom 21.9% had TWF and 34.8% had TWQ categorized as insufficient on B-mode scan of TCCD. On logistic regression, even after adjusting for confounders, age, female sex, pneumatized temporal bone, and temporal bone thickness were independent predictors of TWF. These data may guide to select individuals in whom echogenic contrast or even other imaging methods could be applied to evaluate intracranial vessels.