Haass-Koffler CL, Souza RD, Wilmott JP, et al. - In people who drink heavily (≥ 15 drinks/week for men; ≥ 8 drinks/week for women) and smoke (> 5 cigarettes/day), researchers examined a novel methodological approach to evaluate a simultaneous behavioral alcohol-smoking cue reactivity (CR) paradigm via a human laboratory study. Patients were asked to complete a CR in a bar laboratory as well as an eye-tracking (ET) session using their preferred alcohol beverage, cigarette brand, and water. There was a difference reported in time spent interacting with alcohol and cigarettes vs water, however, there was no difference in time spent interacting between alcohol and cigarettes in both the CR and ET sessions. Cigarette cravings were significantly greater vs alcohol cravings, though only time spent with alcohol, not with cigarettes, was associated with craving for both alcohol and cigarettes, in the CR sessions. Observations suggest the feasibility of using simultaneous cues during a CR procedure in a bar laboratory paradigm. The participants’ decision making in the CR was predicted by the attention bias determined in the integrated alcohol-cigarettes ET procedure. Alcohol cues may influence craving for both alcohol and cigarettes in people who drink heavily and smoke.