Mu L, Liang J, Wang H, et al. - Researchers examined how the association between cognitive function and clinical characteristics of hospitalized patients with schizophrenia differ by sex. They enrolled a total of 251 schizophrenia patients (males/females = 167/84) and 178 healthy controls (males/females = 84/94). The Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) was used to assess cognitive function. Psychiatric symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS). In multivariate regression analyses, there was independent association of attention with negative symptoms in female patients, and with general psychopathology in male patients. In addition, there was independent association of negative symptoms with verbal learning and memory and social cognition only in male patients, while an independent association was observed between general psychopathology and symbol coding only in female patients. These results indicate notable gender disparities in clinical features, cognitive impairment, and their correlations in schizophrenia patients.