Zhang WJ, Wang ZY, Zhou WX, et al. - This study was undertaken to investigate the risk factors for chronic kidney disease (CKD) stage 3 among adults with acquired solitary kidney (ASK) from unilateral nephrectomy. Data were retrospectively obtained from adult patients with ASK between January 2009 and January 2019, distinguished from a tertiary hospital in China. Researchers compared clinical data between patients who developed CKD stage 3 and those who did not develop CKD stage 3 during follow-up. A total of 172 patients with ASK (110 men; median 58.0 years) were included, with a median follow-up duration of 5.0 years. Among adult patients with ASK, regular follow-up of renal function is required. This study's findings demonstrate that optimal management of diabetes, hyperuricemia, and CVD may decrease their risk of CKD stage 3, particularly among those that undergo unilateral nephrectomy for renal tuberculosis.