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Risk factors for the concomitant occurrence of alcoholic chronic pancreatitis and alcoholic liver cirrhosis: A 10-years cohort study at a tertiary hospital in China

European Journal of Gastroenterology & Hepatology Aug 07, 2020

Tan JH, , Jin YC, et al. - This study was undertaken to distinguish the possible risk factors of chronic pancreatitis (CP) and liver cirrhosis (LC) in alcoholic liver cirrhosis (ALC) patients and alcoholic chronic pancreatitis (ACP) patients, respectively. Researchers conducted a retrospective analysis of 536 patients with CP and 647 ALC patients without CP (Group A), then 213 ACP cases were classified into ACP with LC (Group B, n = 52) and ACP without LC (Group C, n = 161) among the 536 CP patients. They compared Group A and B to distinguish the possible risk factors of CP in ALC patients; Group B and C were also compared to ascertain the independent risk factors of LC in ACP patients. It was reported that in ACP patients, HBV infection worsened liver damage and it was the only independent risk factor linked with LC in ACP patients. Study results support that alcoholic patients who smoked and suffered from ongoing bouts of acute pancreatitis tend to develop CP.

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