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The effect of referral to an open‐group behavioural weight‐management programme on the relative risk of normoglycaemia, non‐diabetic hyperglycaemia and type 2 diabetes: Secondary analysis of the WRAP trial

Diabetes, Obesity and Metabolism Jul 28, 2020

Ahern AL, Griffin SJ, Wheeler GM, et al. - This study was intended to evaluate the effect of open‐group behavioural weight‐management programmes on the risk of diabetes among those with a BMI of ≥ 28 kg/m2 and those with non‐diabetic hyperglycaemia (NDH). Researchers conducted a secondary analysis of data from the WRAP trial including a total of 1,267 individuals(N = 1267; aged ≥18 years, BMI ≥ 28 kg/m2) who were randomized to brief intervention (BI; self‐help booklet), a weight‐management programme (WW; formerly Weight Watchers) for 12 weeks, or WW for 52 weeks. The multinomial logistic regression was applied to analyze the impact of intervention group on the risk of hyperglycaemia and diabetes at 12 months in all participants with glycaemic status at both time points (N = 480; 38%) and those with NDH at baseline (N = 387; 31%). The mixed-effects models and linear fixed-effects models were employed to evaluate the impact of intervention group on body weight and HbA1c at 12 months in people with NDH. This study's findings demonstrate that open‐group behavioural weight‐management programmes can help to prevent the development of NDH in people with overweight and obesity and to normalize glycaemia in people with NDH.

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