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The course of asthma: A population‐based 10‐year study examining asthma remission in children diagnosed with asthma in preschool

Pediatric Pulmonology Jun 12, 2020

Oluwole O, Rennie DC, Goodridge D, et al. - Researchers conducted the study for examining predictors of asthma remission with a focus on the age of asthma onset. It was a retrospective birth cohort of children with asthma in Saskatchewan, Canada. Using the databases of the Saskatchewan Ministry of Health, they identified children with a diagnosis of asthma in the first 6 years of life and who had at least 10 years of follow‐up after diagnosis (n = 22,563). Of these, 6,393 children either with persistent asthma (≥ 1 physician visit or hospitalization for asthma [PVHA] during each year of follow‐up) and those who had remission (had PVHA in the first year after diagnosis but at some point during the follow‐up no longer received PVHA until end of the study) were included. The rate of asthma remission was 37 per 100 person‐years over the 10‐years of follow‐up. Remission was positively associated with early-onset asthma, being female, living in rural and medium urban location, while atopy history decreased the likelihood of remission. Most children with asthma experienced remission, particularly those with symptoms onset within the first 3 years of life.

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