Vitale C, Marangella M, Bermond F, et al. - Researchers tried to find out if cholecalciferol supplementation may elevate the risk of stone recurrence in patients with calcium nephrolithiasis and Vitamin D deficiency. A total of 33 stone formers (56 ± 17 years old, 12 males) with 25(OH)D < 20 ng/mL were included in the study. Researchers analyzed calcium excretion and urine supersaturation with calcium oxalate and brushite, both before and after cholecalciferol supplementation. The outcomes of this study demonstrate that cholecalciferol supplementation may elevate calcium excretion, or reveal an underlying condition of absorptive hypercalciuria. This may elevate both urine supersaturation with calcium salts and stone-forming risk.