Gribbons KB, Ponte C, Craven A, et al. - This study was undertaken to determine whether clinical giant cell arteritis (GCA) subsets have distinct profiles or reflect differential diagnostic evaluations. Researchers recruited individuals from an international cohort and classified into 4 subsets based on a temporal artery (TA) abnormality (positive temporal artery biopsy [TAB] or halo sign on TA ultrasound [TA‐US]) and/or evidence of large vessel (LV) involvement on imaging [both TA abnormality and LV involvement (TA+/LV+ GCA), TA abnormality without LV involvement (TA+/LV− GCA), LV involvement without TA abnormality (TA−/LV+ GCA) and clinically diagnosed GCA without LV involvement or TA abnormality (TA−/LV− GCA)]. This study included a total of 941 individuals with GCA from 72 international study sites. The results indicates that vascular imaging is increasingly incorporated into the diagnostic measurement of GCA and distinguishes clinical subsets of individuals based on involvement of temporal and extracranial arteries.