Rakha S, et al. - Researchers determined the acute influence of hemodialysis (HD) on cardiac functions, via conventional echocardiography and two-dimensional (2D) speckle tracking, among pediatric patients with end-stage renal disease (ESRD). They prospectively selected 40 ESRD pediatric patients on chronic HD between June 2018 and April 2019. The mean of the included patients was 12.9 ± 2.9 years, and the sample comprised 24 (60%) males. Findings revealed that in ESRD pediatric patients, 2D speckle tracking could identify post-hemodialysis significant reduction in left ventricular ejection fraction as well as global and segmental strains, despite the nonsignificant alterations in systolic functions derived from conventional echocardiography. This was regarded as additional proof of HD deleterious impact on myocardial functions, especially in the pediatric age.