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Preoperative treatment with ulipristal acetate before outpatient hysteroscopic myomectomy

Gynecologic and Obstetric Investigation Mar 30, 2020

Ferrero S, Scala C, Vellone VG, et al. - As the resection of submucosal myomas is usually performed by hysteroscopy and there is no previous study examining the use of preoperative hormonal therapy before outpatient hysteroscopic myomectomy, researchers here assessed the utility of 3-month preoperative treatment with ulipristal acetate (UPA) prior to outpatient hysteroscopic myomectomy in patients with FIGO (International Federation of Gynecology and Obstetrics) type 0–1 myomas. This prospective patient preference study included 38 women treated with UPA and 45 women who underwent direct surgery. Outcomes suggest that the chance of single-step complete outpatient hysteroscopic resection of single FIGO type 0–1 myoma improves in correlation to receiving three-month UPA treatment. Preoperative UPA treatment reduced the operative time and the volume of fluid infused.

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